M.D., Professor, Johns Hopkins Medical Institutions
James Herman is Professor of Oncology in The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. He is an attending physician at the Johns Hopkins Hospital. He has authored or co-authored more than 290 publications, among which are the most highly cited papers in the field of gene silencing. His lab studies epigenetic changes that are present in human cancer. Initial work focused on the demonstration that changes in promoter region DNA methylation can act as an alternative coding region mutation for tumor suppressor gene inactivation. Current work focuses on the use of epigenetic changes to develop treatment-selection biomarkers.